Methods: H9c2 cardiomyocytes were incubated with GBR at a five ƞg/mL concentration for 24 hours and simulated I/R (sI/R) for 40 minutes.

Thus, this study aims to investigate the cardioprotective effects of GBR pretreatment against simulated I/R injury. However, the effect of GBR mediated cardioprotective properties, focusing on mitochondrial function’s role, remains unexplored.

Germinated Brown Rice (GBR) has been recommended as a bio-functional food and has clarified the potential properties in several effects. The key modulator of I/R injury is dysregulation of mitochondria function. Purpose: Ischemic/reperfusion (I/R) injury is the principal mechanism during Ischemic Heart Disease (IHD). Kanokwan Demeekul, 1 Wichit Suthammarak, 2 Soontaree Petchdee 3ġGraduate School, Program of Bio-Veterinary Science, Kasetsart University, Kamphaeng Saen, Nakorn Pathom, Thailand 2Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand 3Department of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen Campus, Nakorn Pathom, Thailandĭepartment of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen, Nakorn Pathom, 73140, Thailand

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